• The exact causes of the chromosomal rearrangement and primary prevention of Down syndrome are currently unknown.
• Down syndrome is one of the leading clinical causes of cognitive delay in the world--it is not related to race, nationality, religion or socio-economic status.
• The incidence of Down syndrome in the United States is approximately one in every 800-1,000 live births.
• Of all children born in this country annually, approximately 5,000 will have Down syndrome.
• There are approximately 1/4 million families in the United States affected by Down syndrome.
• While the likelihood of giving birth to a child with Down syndrome increases with maternal age, 80% of babies with Down syndrome are born to women under 35 years of age, as women in that age group give birth to more babies overall.
• There is a wide variation in cognitive abilities, behavior, and physical development in individuals with Down syndrome. Each individual has his/her own unique personality, capabilities and talents.
• 30%-50% of individuals with Down syndrome have heart defects and 8%-12% have gastrointestinal tract abnormalities present at birth. Most of these defects are now correctable by surgery.
• Individuals with Down syndrome benefit from loving homes, early intervention, inclusive education, appropriate medical care and positive public attitudes.
• In adulthood, many persons with Down syndrome hold jobs, live independently and enjoy recreational opportunities in their communities.

Need more information? Contact the Down Syndrome Resource Center